Unexplained Infertility 


Unexplained infertility, the condition where the cause of infertility could not be identified is called unknown or unexplained infertiliy, although normal sperm analysis was performed, ovulation was proven to occur, intrauterine check was performed, the fallopian tubes were checked and all the results came back normal. The cause of infertility cannot be determined in about 10-20% of the couples diagnosed with infertility.

In unknown infertility, the duration of infertility and the age of woman are important in terms of reproductive capacity and duration of response to treatment. In unknown infertility, pregnancy occurs within years without initiating any treatment.


Unexplained infertility, however, since the passing time increases the risk of inability to conceive, treatment should be initiated without losing time. For example, the risk of inability to conceive increases by 1-2% every month for a couple who has been infertile for 3 years, and this rate increased by 10% every year if a woman’s age is above 30 years. The treatment administered aims to increase the monthly conception rate to the level of normal couples.

Unexplained Infertility Açıklanamayan Kısırlık

What is the Cause of Unknown Infertility?

Hence the name, the cause of infertility cannot be determined despite all examinations. This does not mean that there is no cause of infertility, but means that the causes cannot be revealed with today’s possibilities.

Unexplained infertility, it is thought that molecular problems in female eggs or male eggs, as well as immunological, genetic or coagulation problems, which cannot be determined today, may cause infertility.

Unexplained infertility, with the developing technology, it is certain that this issue will also be clarified.

What are the treatment methods for unknown infertility?

In unknown infertility, there is no commonly used treatment method. As the cause of infertility cannot be identified, the treatments administered aim to increase the number of eggs and sperm meeting. Some of the couples diagnosed with infertility may naturally achieve pregnancy within 1-3 years. In cases of not being able to get pregnant, patients are first recommended to use drugs that increase the number of eggs. Afterwards, insemination method, the method of preparing the sperms taken from the male in the laboratory and placing into the uterus, is tried.

Unexplained Infertility

In cases where no result is obtained from ovulation and insemination methods, IVF method is recommended to patient. In vitro fertilization is a method of fertilizing sperm and eggs in the laboratory and injecting them into the uterus. In recent years, this method has been significantly developed and has been highly successful with additional in vitro fertilization methods (micro-TESE, micro injection), and many families diagnosed with infertility have had a child.


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